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Autodesk Inc master mold of microfluidic chip
Concept design of liver-on-chip via femtosecond laser patterning. (A) Schematic illustrations of minimum functional unit of the in vivo liver (i.e., hepatic lobule), which is composed of a dense-hepatocyte tissue (brown) and a microvascular network (red). (B) Construction of the hepatic lobule-like structure in a <t>microfluidic</t> chip. (C) Fabrication process of the liver-on-chip via high-definition (HD) laser patterning. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Master Mold Of Microfluidic Chip, supplied by Autodesk Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/master+mold+of+microfluidic+chip/pmc11979415-44-4-10?v=Autodesk+Inc
Average 90 stars, based on 1 article reviews
master mold of microfluidic chip - by Bioz Stars, 2026-08
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1) Product Images from "Advanced liver-on-chip model mimicking hepatic lobule with continuous microvascular network via high-definition laser patterning"

Article Title: Advanced liver-on-chip model mimicking hepatic lobule with continuous microvascular network via high-definition laser patterning

Journal: Materials Today Bio

doi: 10.1016/j.mtbio.2025.101643

Concept design of liver-on-chip via femtosecond laser patterning. (A) Schematic illustrations of minimum functional unit of the in vivo liver (i.e., hepatic lobule), which is composed of a dense-hepatocyte tissue (brown) and a microvascular network (red). (B) Construction of the hepatic lobule-like structure in a microfluidic chip. (C) Fabrication process of the liver-on-chip via high-definition (HD) laser patterning. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Figure Legend Snippet: Concept design of liver-on-chip via femtosecond laser patterning. (A) Schematic illustrations of minimum functional unit of the in vivo liver (i.e., hepatic lobule), which is composed of a dense-hepatocyte tissue (brown) and a microvascular network (red). (B) Construction of the hepatic lobule-like structure in a microfluidic chip. (C) Fabrication process of the liver-on-chip via high-definition (HD) laser patterning. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)

Techniques Used: Functional Assay, In Vivo

Construction of continuous microvessels in the laser-patterned microchannels. (A) Schematic illustrations of microvessel formation in the laser-patterned microchannels with different diameters (i.e., Ø50 and Ø80 μm) in the cell-containing hydrogel. RFP-HUVECs were seeded to one side channel of the microfluidic chip. (B) Fluorescence images of RFP-HUVECs (red) in the laser-patterned on days 5 and 9. The cross-view images correspond to the dotted lines (i–iii) in the above image. Scale bars: 200 μm. (C) Quantitative analysis of length of continuous microvessel on days 5 and 9. Data represent the mean ± SD (n = 18/group). ∗ p < 0.05 (two-way ANOVA with the post hoc Tukey's honestly significant difference test). (D) Quantitative analysis of width of microvessel on days 5 and 9. Data represent the mean ± SD (n = 18/group). ∗ p < 0.05 (Student's t -test). Blue lines indicate 50 μm and 80 μm in width of microvessel, respectively. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Figure Legend Snippet: Construction of continuous microvessels in the laser-patterned microchannels. (A) Schematic illustrations of microvessel formation in the laser-patterned microchannels with different diameters (i.e., Ø50 and Ø80 μm) in the cell-containing hydrogel. RFP-HUVECs were seeded to one side channel of the microfluidic chip. (B) Fluorescence images of RFP-HUVECs (red) in the laser-patterned on days 5 and 9. The cross-view images correspond to the dotted lines (i–iii) in the above image. Scale bars: 200 μm. (C) Quantitative analysis of length of continuous microvessel on days 5 and 9. Data represent the mean ± SD (n = 18/group). ∗ p < 0.05 (two-way ANOVA with the post hoc Tukey's honestly significant difference test). (D) Quantitative analysis of width of microvessel on days 5 and 9. Data represent the mean ± SD (n = 18/group). ∗ p < 0.05 (Student's t -test). Blue lines indicate 50 μm and 80 μm in width of microvessel, respectively. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)

Techniques Used: Fluorescence



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Autodesk Inc master mold of microfluidic chip
Concept design of liver-on-chip via femtosecond laser patterning. (A) Schematic illustrations of minimum functional unit of the in vivo liver (i.e., hepatic lobule), which is composed of a dense-hepatocyte tissue (brown) and a microvascular network (red). (B) Construction of the hepatic lobule-like structure in a <t>microfluidic</t> chip. (C) Fabrication process of the liver-on-chip via high-definition (HD) laser patterning. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Master Mold Of Microfluidic Chip, supplied by Autodesk Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/master+mold+of+microfluidic+chip/pmc11979415-44-4-10?v=Autodesk+Inc
Average 90 stars, based on 1 article reviews
master mold of microfluidic chip - by Bioz Stars, 2026-08
90/100 stars
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Concept design of liver-on-chip via femtosecond laser patterning. (A) Schematic illustrations of minimum functional unit of the in vivo liver (i.e., hepatic lobule), which is composed of a dense-hepatocyte tissue (brown) and a microvascular network (red). (B) Construction of the hepatic lobule-like structure in a microfluidic chip. (C) Fabrication process of the liver-on-chip via high-definition (HD) laser patterning. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)

Journal: Materials Today Bio

Article Title: Advanced liver-on-chip model mimicking hepatic lobule with continuous microvascular network via high-definition laser patterning

doi: 10.1016/j.mtbio.2025.101643

Figure Lengend Snippet: Concept design of liver-on-chip via femtosecond laser patterning. (A) Schematic illustrations of minimum functional unit of the in vivo liver (i.e., hepatic lobule), which is composed of a dense-hepatocyte tissue (brown) and a microvascular network (red). (B) Construction of the hepatic lobule-like structure in a microfluidic chip. (C) Fabrication process of the liver-on-chip via high-definition (HD) laser patterning. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)

Article Snippet: A master mold of microfluidic chip was designed in AutoCAD (Autodesk, San Francisco, CA, USA) in order to realize the millimeter-scale hepatic lobule in the central channel of the chip.

Techniques: Functional Assay, In Vivo

Construction of continuous microvessels in the laser-patterned microchannels. (A) Schematic illustrations of microvessel formation in the laser-patterned microchannels with different diameters (i.e., Ø50 and Ø80 μm) in the cell-containing hydrogel. RFP-HUVECs were seeded to one side channel of the microfluidic chip. (B) Fluorescence images of RFP-HUVECs (red) in the laser-patterned on days 5 and 9. The cross-view images correspond to the dotted lines (i–iii) in the above image. Scale bars: 200 μm. (C) Quantitative analysis of length of continuous microvessel on days 5 and 9. Data represent the mean ± SD (n = 18/group). ∗ p < 0.05 (two-way ANOVA with the post hoc Tukey's honestly significant difference test). (D) Quantitative analysis of width of microvessel on days 5 and 9. Data represent the mean ± SD (n = 18/group). ∗ p < 0.05 (Student's t -test). Blue lines indicate 50 μm and 80 μm in width of microvessel, respectively. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)

Journal: Materials Today Bio

Article Title: Advanced liver-on-chip model mimicking hepatic lobule with continuous microvascular network via high-definition laser patterning

doi: 10.1016/j.mtbio.2025.101643

Figure Lengend Snippet: Construction of continuous microvessels in the laser-patterned microchannels. (A) Schematic illustrations of microvessel formation in the laser-patterned microchannels with different diameters (i.e., Ø50 and Ø80 μm) in the cell-containing hydrogel. RFP-HUVECs were seeded to one side channel of the microfluidic chip. (B) Fluorescence images of RFP-HUVECs (red) in the laser-patterned on days 5 and 9. The cross-view images correspond to the dotted lines (i–iii) in the above image. Scale bars: 200 μm. (C) Quantitative analysis of length of continuous microvessel on days 5 and 9. Data represent the mean ± SD (n = 18/group). ∗ p < 0.05 (two-way ANOVA with the post hoc Tukey's honestly significant difference test). (D) Quantitative analysis of width of microvessel on days 5 and 9. Data represent the mean ± SD (n = 18/group). ∗ p < 0.05 (Student's t -test). Blue lines indicate 50 μm and 80 μm in width of microvessel, respectively. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)

Article Snippet: A master mold of microfluidic chip was designed in AutoCAD (Autodesk, San Francisco, CA, USA) in order to realize the millimeter-scale hepatic lobule in the central channel of the chip.

Techniques: Fluorescence